Javier is right. If you are looking for a high score, you want to go for multiple orange orbs. They build up and carry over to the next game. But for me, the point of playing the game is to pick up an easy 3000 points to invest in neostocks. In fact, after I get to a 1000 in a game, I usually sit under some bombs just to end it.
Here are the “secrets” to getting to 1000 points on a game.
First: get control of the center of the board as soon as possible. Bomb the bugs between the two center barriers before you do anything else. You’ll have to duck under a barrier now and again.